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Increasing food production in the face of a growing population, while adapting to and mitigating climate change constitutes a main challenge for the global agricultural sector. This study identifies, analyses and contextualizes regional initiatives related to agriculture and climate change in developing countries. In order to identify needs for improvements and possibilities for replication or scale-up, a review of recently launched initiatives is combined with a SWOT analysis. Moreover, the study places initiatives in the context of INDCs of Sub-Saharan African countries submitted under the UNFCCC. As a result, recommendations on how to develop and implement best practice agriculture climate change initiatives are presented.